A Study on Lipid Level and It's Effect on Insulin Treatment in Patients with Nonobese Non-Insulin-Dependent Diabetes Mellitus(NNIDDM)

It is well kown that an increased incidence of atherosclerosis in diabetic patients, and hyperlipemia might contribute to its development. Although diabetic populations are increasing in Korea, there are few reports showing abnonmalities of serum lipid metabolism in these patients. Various lipid values in serum were measured in 22 NIDDM and impaired with those of 20 normal control group to assess abnormalities of lipid metabolism. Follwoing results are obtained ; 1) Total lipid concentration was significantly higher in diabetics than in normal control(P<0.01). After control of hyperglycemia, total lipid concentration was significantly decreased(P<0.05). 2) Triglyceride concentration was significantly higher diabetics than in normal control(p<0.01). After control of hyperglycemia, its concentraion was significantly decreased(P<0.05). 3) Total cholesterol concentration was higher in diabetics than normal control, but there were no statistical significances. After control of hyperglycemia, there were on difference among each group.