Original Article

Experimental Study on Microvascular Anastomosis without Sutures Using Fibrin Glue

Chin Ho Yoon, Han Joong Kim
Author Information & Copyright
Department of Plastic Surgery, College of Medicine, Ewha Womans University, Korea.
Corresponding author: Han Joong Kim. Department of Plastic surgery, College of Medicine, Ewha Womans University, Korea.

Copyright ⓒ 1988. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Since the anastomosis by suture, most widely used in microvascular surgery, has two major disadvantage in that it may inflict considerable damage on the vessel ends and that the suture material may function as a thrombogenic agent, much effort has been spent in developing methods of anastomosis in which the number of suture is reduced to minimum. As one of such efforts, we performed the following experiment using fibrin glue leaving out any suture material. First we divided the femoral artery of the rat and telescoped the proximal end into distal end by traction of two U-shaped guide sutures. Next, we removed the guide sutures and dropped the fibrinogen and thrombin solution dissolved in the distilled water and calcium chloride respectively on the telescoped area. After waiting for 5 minutes, vascular clamps were released. The result we got from the gross and histological examination showed that this method has advantage as follows; 1)This method is easier and speedier than suture technique. 2)Suture material was not exposed into the lumen. 3)There was less vessel trauma owing to fewer sutures and less manipulation of the vessel end. 4)Blood leakage from the anastomosal site was prevented. 5)There was no aneurysm.