Original Article

Change of Biogenic Amine Contents in Lead Intoxicated Rat Brain

Kyung Gyu Choi, Byung-Chul Lee**
Author Information & Copyright
Department of Internal Medicine, Ewha Women's University, College of Medicine, Korea.
**Department of Neurology, Hallyn University, College of Medicine, Korea.

Copyright ⓒ 1992. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015


Lead is an neurotoxic substance and its clinical effect on the central nervous system has been well known since several decades ago. As the development of industry becomes more rapid and widespread in the world, we can expect the amount of lead and its harmful effect On the human life would increase in the future. We think the behavioural effect of lead on the central nervous system might be the result of the change of the neurotransmitters in the central nervous system. We studied the change of neurotransmitter amount in the cnetral nervous system of rats after lead intoxication. There was a significant neurotransmitter(catecholamine and 5 hydroxytryptamine) change after lead intoxication in our study.


We are pleased to announce the recent appointment of Dr. Sun Huh as the new editor-in-chief, starting in September 2023. Dr. Ryung-Ah Lee, who previously served as editor-in-chief, dedicated over a decade to her role from January 2013 to August 2023. Her diligent efforts were instrumental in establishing a robust and contemporary system for journal submission and publishing.

Dr. Sun Huh, a former President of the Korean Association of Medical Journal Editors (KAMJE), has graciously accepted the position at Ewha Medical Journal. You can explore his mission and goals as the editor-in-chief of EMJ in the editorial featured in this issue.

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