Original Article

Evaluation of Microparticle Enzyme Immunoassay (MEIA) (ImRx, Abbott) in the Determination of Serum Thyrotropin (TSH)

Ki Sook Hong
Author Information & Copyright
Department of Clinical Pathology, College of Medicine, Ewha Womans University, Korea.

Copyright ⓒ 1993. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015


Microparticle enzyme immunoassay (MEIA) for thyrotropin (TSH) was evaluated and results were compared with those of immunoradiometric assay (IRMA) procedure. Coefficient of variations of within day precision was 3.8-9.6% and those of between day precision was 3.6-17.2%. Correlation between the MEIA(Y) and two site IRMA(X) was excellent (Y=1.0445X-0.1538, r=0.9948). The sensitivity of the assay (mean±2 SD of the zero standard) was 0,0158 µIU/ml. The concentration measured in 497 healthy subjects were ranged from 0.2-3 µIU/ml (mean 1.37 µIU/ml, SD 0.59).

Conclusively, MEIA is more fully automated than IRMA, well correlated with IRMA, can be reliable method for screening test of thyroid function.


We are pleased to announce the recent appointment of Dr. Sun Huh as the new editor-in-chief, starting in September 2023. Dr. Ryung-Ah Lee, who previously served as editor-in-chief, dedicated over a decade to her role from January 2013 to August 2023. Her diligent efforts were instrumental in establishing a robust and contemporary system for journal submission and publishing.

Dr. Sun Huh, a former President of the Korean Association of Medical Journal Editors (KAMJE), has graciously accepted the position at Ewha Medical Journal. You can explore his mission and goals as the editor-in-chief of EMJ in the editorial featured in this issue.

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