Original Article

The Immunohistochemical and Electron Microscopic Observation of Metastatic Small Cell Lung Cancer of Liver

Sun Hee Roh, Kyu Won Chung, Jae Jung Park, Suh Eun Bae, Il Hwan Moon, Kwon Yoo, Min Sun Cho**
Author Information & Copyright
Department of Internal Medicine, Ewha Medical Research Institute, Korea.
**Department of Pathology, Ewha Womans University School of Medicine, Korea.
Corresponding author (kwchung@ewha.ac.kr)

Copyright ⓒ 2009. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Mar 31, 2009

Abstract

Small cell lung cancer accounts for about 20% of all lung cancers. At the time of diagnosis, the majority of patients already have metastasis. The liver is one of the most common sites of distant metastasis of lung cancer. Small cell lung cancer arises from neuroendocrine cells which produce hormone, hormone producing granules can be seen under electron microscope . A 65-year-old male was admitted to hospital because of jaundice and right upper quadrant pain. The chest roentgenogram and chest computed tomography(CT) scan showed a 3 cm mass in right upper lobe with bilateral mediastinal lymphadenopathy and right pleural effusion. The abdomen CT scan revealed multiple masses in the liver with heterogenous pattern suggesting metastatic orgin. Though the immunohistochemistry and electron miscroscopy, he was diagnosed as metastatic small cell lung cancer of liver. We report a case of the Immunohistochemical and Electron Microscopic Observation of Metastatic Small Cell Lung Cancer of Liver.

Keywords: Lung cancer; Liver metastasis; The immunohistochemical and electron microscopic observation