Case Report

The Mixed Hepatocellular-Cholangiocarcinoma Confirmed by Liver and Neck Node Biopsy

Hye Won Kang, Jae Jung Park, Il Hwan Moon, Seo Woo Kim, Hyun Kyung Kim, Hyun Jung Oh, Go Heun Kim, Yoon Jung Choi, Hyun Mi Huh, Young Wook Roh, Tae Hun Kim, Kwon Yoo, Ji Yoon Bae**, Dong Eun Song**
Author Information & Copyright
Department of Internal Medicine, Ewha Womans University School of Medicine, Korea.
**Department of Pathology, Ewha Womans University School of Medicine, Korea.
Corresponding author (ihmoon@ewha.ac.kr)

Copyright ⓒ 2009. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Sep 30, 2009

Abstract

Mixed hepatocellular-cholangiocarcinoma accounts for about 1% of all hepatocellular carcinoma. In many cases, mixed hepatocellular-cholangiocarcinoma has been misdiagnosed as hepatocellular carcinoma or cholangiocarcinoma because of the indistinctive clinical course and radiologic findings. The clinical course and the pathologic characters are not known well, but it resembles the characteristics of hepatocellularcarcinoma rather than cholangiocarcinoma. So mixed hepatocellular-cholangiocarcinoma was classified as a kind of hepatocellular carcinoma. But the growth and dissemination rate is faster than that of hepatocellular carcinoma and the prognosis more poor. So the exact diagnosis is important. Authors experienced a patient who has the mixed hepatocellular-cholangiocarcinoma diagnosed by liver and neck node biopsy in patient who complain-ed abdominal discomfort and palpable mass, so we report the case.

Keywords: Mixed hepatocellular-cholangiocarcinoma; Immunohistochemistry