The Histopathologic Observation of Necrotizing Lymphadenitis

Since 1972, the necrotizing lymphadenitis, histiocytic necrotizing lymphadenitis without granulocytic infiltration etc. Seven cases of necrotizing lymphadenitis has presented in this study. Most of them were young men characterized by persistent lymphadenopathy with or without fever. The histopathologic features of lymphnodes showed focal or diffuse well circumscribed paracortical necrotizing lesion, abundant karyorrhectic debris and aggregates of large mononuclear cells. However, there were no infiltrates of plasma cells and neutrophils. The remaining areas of lymphnodes showed severe degree of paracortical hyperplasia without significant hyperplasia of lymphoid follicles in the cortex.