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The Ewha Medical Journal
Ewha Womans University School of Medicine

Ewha Med J 1990; 13(1):11-19

pISSN: 1598-7450

DOI: https://doi.org/10.12771/emj.1990.13.1.11

Original Article

Experimental Study of Chronic Cerebral Spasm

Kyu Man Shin

Copyright ⓒ 1990. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

For the purpose of the study of severity of the chronic vasospasm after subarachnoud hemorrhage(SAH), SAH was induced in dogs by injections of fresh unheparinized autologous arterial blood into the cisterna magna. The experimental groups were devided into two groups. Group I was that of the only one 5ml injection of subarachnoid blood, and Group II was that of the double-hemorrhage canine model; secondary injection of 3ml at 24hours after initial injection. Selective left vertebral angiograms were performed 5 days before and 7 days after the initial SAH and were compared to determine the percentage of reduction in basilar artery diameters. The reductions in basilar artery diameter of Group I and II were 33.0%±0.90 and 45.3%±1.99 respectively.

This result suggest that the severity of spasm is related to the volume of hemorrhage and rebleeding episode.