The Ewha Medical Journal
Ewha Womans University School of Medicine
Original Article

Changes on the Serum Immunoglobulin M Levels of Mother and Cord in Term Pregnancy

Jung Ja Ahn

Copyright ⓒ 1991. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

This study was undertaken to determine whether any chenges occur in the serum levels of immunoglobulin M(IgM) of mother and cord in term pregnancy.

IgM levels were measured in paired maternal and cord serum samples from 6 pregnancies with intrauterine growth retardation(IUGR) and 42 with normal growth(adequate-for-gestational age(AGA) pregnacies) delivered at term gestation during the period from January. 1989 to June. 1989 at the Ewha Womans University Hospital.

The results obtained were as follows ;

1) Serum IgM levels of mother who delivered IUGR infants were found significantly higher than those who delivered AGA infants.

2) There were no significant differences in the maternal serum IgM levels of the four groups(38 weeks' gestation. 39 weeks' gestation. 40 weeks' gestation. and 41 or more weeks' gestation).

3) There was no significant difference in the serum IgM levels between mother delivered male infant and female infant.

4) There was no significance between the maternal serum IgM levels and the birth weight of baby, although the maternal serum IgM levels had decreased tendency gradually as the birth weights of the baby were increased.

5) Cord serum IgM levels of IUGR infant were not significantly different from those of AGA infant.

6) The cord serum IgM levels were not related to the maternal werum IgM levels in term pregnancy.