The Ewha Medical Journal
Ewha Womans University School of Medicine
Original Article

A Case of Trisomy 16 was Discovered with Missed Abortion after in Vitro Fertilization and Embryotransfer

In Ok Song, Hye Won Chung, Young Soo Son, Sun Hee Chun, Bock Hi Woo, Seong Eun Oh

Copyright ⓒ 1993. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015


We experienced a case of trisomy 16 discovered with missed abortion in pregnancy achievedby IVF-ET. Spontaneous abortion rate after IVF-ET was higher than normal pregnancy. Chro-mosome anomalies had been reported in spontaneous abortions after IVF-ET. We had attempted to karyotype which miscarriged gestational 8 weeks, and the result was found trisomy 16.So we reported the case with a brief review of literatures.