The Ewha Medical Journal
Ewha Womans University School of Medicine
Original Article

Retinal Changes after Replacement of Vitreous with Perfluorodecalin

Young Bock Han

Copyright ⓒ 1994. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Dec 31, 1994


Retinal changes were evaluated after vitreous replacement with perfluorodecalin. Tolerance to this liqued in rabbit eyes was investigated for peiod of 1 month.

Histologic examination revealed degeneration the loss of the outer segment of the photoreceptors, decreased thickness of the outer retinal layers and in the vitreous These changes were progressed with the longer duration of the intravitreal replacement of perfluorodecalin. From the above resulgts, perfluorodecalin is thought to be unsuttable for the long-term witreous substitute and should be removed from the wyw before the vompletion of surgery.