The Ewha Medical Journal
Ewha Womans University School of Medicine
Case Report

A Case of Mixed Connective Tissue Disease

Yoo Won Choi, Hae Young Choi, Ki Bum Myung

Copyright ⓒ 1995. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015


We report a case of mixed connective tissue disease in a 35-year-old woman showing typicallaboratory and clinical features. Clinically she suffered from hand edema, arthritis, proximalmuscle weakness, loss of hair and Raynaud's phenomenon. FANA revealed a speckled epidermal nuclear staining pattern. Analysis of serum showed anti RNP antibody positive and antiSm antibody negative. Anti DHA antibody occurred in low titer. The patient showed a promptreponse to prednisone 0.5mg per body weight without any recurrence.

Keywords: Mixed connective tissue disease; Anti RNP Antibody