Table 3
Relationship between EGFR mutation and the clinicopathologic features

Variable	Number	EGFR* mutation (%)	P value
Age (year)
<60	19	5 (26.32)	0.74
≥60	39	8 (20.51)
Gender
Male	35	10 (28.57)	0.21
Female	23	3 (13.04)
CEA (ng/mL)
5≤	41	9 (21.95)	1
>5	17	4 (23.53)
CA19-9 (U/mL)
27≤	51	12 (23.53)	1
>27	7	1 (14.29)
Stage
Tis†~II	33	11 (33.33)	0.028
III~IV	25	2 (8.00)
Location
Colon	37	9 (24.32)	0.751
Rectum	21	4 (19.05)
Differentiation
Well	8	0 (0)	0.267
Moderate	45	12 (26.67)
Poor	5	1 (20.00)
LN‡ metastasis
Absent	33	11 (33.33)	0.028
Present	25	2 (8.00)

EGFR, epithelial growth factor receptor; ^†Tis, tumor in situ; ^‡LN, lymph node.