Table 2. Studies dealing with the occurrence of acute kidney injury among colorectal surgery patients receiving enhanced recovery after surgery perioperative care

 Author Year Study design Group No. of patients Population AKI (%) LOS (days) LOS (days) of AKI patients vs. non-AKI in ERAS group Other significant factors for AKI
Marcotte et al. [12] 2018 Retrospective cohort ERAS vs. matched pre-ERAS 132 vs. 132 Colorectal resection (laparoscopy: 72.3%) 11.4 vs. 2.3, P<0.0001 5.5 vs 7.7, P<0.0001 8.40 vs. 5.11 (P=0.0037)
Wiener et al. [13] 2020 Retrospective cohort ERAS vs. pre-ERAS (in the NSQIP registry) 572 vs. 480 Colorectal resection 13.64 vs. 7.08, (OR 2.31, 95% CI 1.48−3.59, P<0.01) 7 (5−12) vs. 3 (2−6), P<0.01 Median 4 (IQR 4–9) vs. 3 (2–5), P=0.04 Smoking, ASA grade ≥3
Drakeford et al. [14] 2022 Retrospective cohort AKI vs. non-AKI n=555 Colorectal surgery +ERAS 13.4 (stage I: 11.2%, II: 2.0%, III: 0.2%) Median 11 (IQR 5−17) vs. 6 (4−8), P<0.001 High preoperative creatinine level, open surgery, long anesthesia duration, major complications
Shim et al. [15] 2020 Retrospective cohort (Intraoperative) oliguria* vs. matched non-oliguria 125 vs. 125 Laparoscopic colorectal cancer resection+ERAS 26.4 vs. 11.2, (OR 2.708, 95% CI 1.354−5.418, P=0.005)
AKI, acute kidney injury; LOS, length of hospital stay; ERAS, enhanced recovery after surgery; NSQIP, National Surgical Quality Improvement Program; ASA, American Society of Anesthesiologists.
Defined as <0.5 mL/kg/h.