The Ewha Medical Journal
Ewha Womans University School of Medicine
Case Report

A Case of Reactive Perforation Collagenosis

Hyun Ok Kim, Hai Min Choi, Hong Il Kook

Copyright ⓒ 1990. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015


In 1967, Mehregan et al described a new and distinct clinicopathologic entily that called reactive pergorating collagenosis. This rare disease is classfied with a group of disorders that involve the transepithelial elimination of hestochemically altered dermal tissue. In reactive perforating collagenosis, minor trauma such as an insect bite, scratch, or pliodrbaceous infection alters the collagen fibers in the dermis. We report here a case of reactive perforating collagenosis in a 54-year-old female patient without any associated disseases of specific family history.