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"Acute kidney injury"

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"Acute kidney injury"

Case Reports
[English]
Severe Acute Kidney Injury with Familial Renal Hypouricemia Confirmed by Genotyping of SLC22A12
Chang Min Cho, Hae Il Cheong, Jung Won Lee
Ewha Med J 2020;43(2):35-38.   Published online April 30, 2020
DOI: https://doi.org/10.12771/emj.2020.43.2.35

Idiopathic renal hypouricemia is a hereditary disease characterized by abnormally high renal uric acid clearance. A defect in the SLC22A12 genes, which encodes the renal uric acid transporter, URAT1, is the known major causes of this disorder. Most patients are clinically silent, but exercise-induced acute kidney injury, urolithiasis or hematuria may develop. The patient presented with azotemia, decreased urine output and abdominal pain without vigorous exercise past history. He was diagnosed with rapidly progressive glomerulonephritis at admission, but low serum uric acid level was persisted. Since the diagnosis of the patient was familial renal hypouricemia, we performed sequence analysis of the SLC22A12 gene in all family members. We report a case of 17-year-old boy with severe acute kidney injury with familial renal hypouricemia confirmed by genotyping of SLC22A12.

Citations

Citations to this article as recorded by  
  • Renal hypouricemia type 2 with SLC2A9 compound heterozygous variants: a case report of recurrent acute kidney injury triggered by low-intensity exercise
    Niranjana Rekha Paladugu, Muralinath Vukkadala
    Frontiers in Nephrology.2024;[Epub]     CrossRef
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  • 1 Crossref
[English]
Malignant Hypertension with Pulmonary Alveolar Hemorrhage Needing Dialysis
Younghun Kim, Ki Tae Bang, Jong Ho Shin, Ju Ri Kim, Joo Heon Kim, Jin Uk Jeong
Ewha Med J 2017;40(2):87-90.   Published online April 28, 2017
DOI: https://doi.org/10.12771/emj.2017.40.2.87

A 35-year-old man presented with progressive dyspnea and hemoptysis. His blood pressure was 230/140 mmHg and serum creatinine level was 20.13 mg/dL. Chest radiography and computed tomography revealed pulmonary hemorrhage. His renal function was low, thus emergent renal replacement therapy was required. Malignant hypertension and acute kidney injury were diagnosed, and antihypertensive therapy and hemodialysis started immediately. Renal biopsy was performed to examine the underlying disease. Typical pathological changes of malignant hypertension, fibrinoid necrosis of the afferent arterioles, and proliferative endoarteritis at the interlobular arteries were observed. His renal function improved gradually and pulmonary hemorrhage completely disappeared with administration of antihypertensive agents. Here, we report this rare case of malignant hypertension with pulmonary alveolar hemorrhage and speculate that the hemorrhage may be related to vascular injuries at the alveolar capillary level caused by malignant hypertension.

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[English]
Atypical Kawasaki Disease Presenting as Acute Kidney Injury in a Patient with Influenza B Virus Infection
Ye Jin Han, Sung Jin Kim, Ji Hei Cha, Seung Joo Lee, Sejung Sohn
Ewha Med J 2015;38(2):80-84.   Published online July 29, 2015
DOI: https://doi.org/10.12771/emj.2015.38.2.80

Influenza virus infection is a common respiratory disease in children. Renal complications of influenza infection were not commonly encountered until the 2009 H1N1 influenza pandemic, when acute kidney injury (AKI) frequently developed in severely ill patients. Kawasaki disease (KD) is another rare association in pandemic influenza virus infections. There are some reports about KD coincident with influenza A H1N1/09 infection. However, simultaneous AKI and KD in influenza A or B virus infections have never been reported. Herein, we report the first case of influenza B virus infection that initially presented as AKI but was subsequently diagnosed as atypical KD.

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[English]
Renal Parenchymal Malakoplakia with Acute Interstitial Nephritis Presented with Acute Kidney Injury
In Mee Han, Youn Kyung Kee, Eunyoung Lee, Choong-kun Lee, Seung Gyu Han, Su Jin Heo, Tae-Hyun Yoo
Ewha Med J 2015;38(1):36-41.   Published online March 26, 2015
DOI: https://doi.org/10.12771/emj.2015.38.1.36

Malakoplakia is an uncommon chronic granulomatous inflammatory disease which is associated with immunocompromised conditions such as malignancy, autoimmune disease, chronic alcohol intake, poorly controlled diabetes and long-term steroid use. Malakoplakia can occur at various sites, most commonly in the genitourinary tract including urinary bladder and the ureter. Renal parenchymal involvement is relatively uncommon, accounting for 15% of all malakoplakia. A few cases of renal malakoplakia have been reported in Korea, and only one case was accompanied by acute kidney injury. Here we report an 80-year-old female patient with renal parenchymal malakoplakia and acute interstitial nephritis presented as acute kidney injury with literature review.

Citations

Citations to this article as recorded by  
  • Impact of underlying diseases and complications on COVID-19 mortality in South Korea: analysis of national health insurance service data
    Kyunghee Lee, Jieun Hwang
    Archives of Public Health.2025;[Epub]     CrossRef
  • Bladder Malakoplakia Mimicking Bladder Cancer
    Hak Soo Kim, Soo Yong Choi, Sung Eun Kim, Kihoon Lee, Hyun Ju Lee, Gil Hyun Kang, Hoon Yu
    The Korean Journal of Medicine.2017; 92(5): 476.     CrossRef
  • 117 View
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  • 2 Crossref
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