Dystrophic calcinosis of scrotal wall, consisting of solitary or multiple circumscribed calcium deposits in previously damaged tissue, such as sebaceous cyst, xanthoma, fibroma, dartos muscle, onchocerciasis, trichilemmal cyst and epidermal cyst, may itch or drain chalky white material. The twenty-one years old male patient had multiple, 2 to 4mm sized yellowish or flesh colored papules in scrotal wall. Histopathologically each papule showed intact epidermal cyst or keratinous material with calcium deposits within the epidermal cyst which is partially degenerated and surrounded foreign body reaction. Therefore, we report a case of dystrophic scrotal calcinosis associated with the inflammation of scrotal epidermal cyst.