, Sung-Ae Jung, Seong-Eun Kim, Jong Soo Lee, Seung Hyun Nam, Jeong Eun Shin, Hae Sung Moon, Seung Cheol Kim, Kwon Yoo In Lynch syndrome II, colon cancer was associated with endometrial and ovarian cancer. The aim of this study was an evaluation for the clinicopathologic characteristics of rectosigmoid adenomas on preoperative sigmoidoscopy in gynecologic cancer patients.
A total 187 gynecologic cancer patients(139 cervical, 35 ovarian, 13 endometrial cancer) and 58 normal controls were reviewed sigmoidscopic finding and pathologic reports retrospectively from September 1993 to March 2001.
The mean age of gynecologic cancer patients was 54(38-82) year-old and normal controls was 50(20-68) year-old. Total 26 adenomas were in 21 patients(11.2%) and 3 adenomas were in 3 normal controls(5.2%). The incidence of adenomas was 9.4% in cervical cancer, 8.6% in ovarian cancer and 38.5% in endometrial cancer. Multiple adenomas were in 5 gynecologic cancer patients and 0 normal controls. The incidence of advanced adenoma was 12.5% in cervical cancer, 25.5% in ovarian cancer, 83.5% in endometrial cancer and 33.3% in normal controls. The location of adenoma was 23.1% in rectum and 76.9% in sigmoid colon.
The incidence of adenomas and multiple adenomas were higher in gynecologic cancer patients than normal controls but not significantly. The incidence of advanced adenoma and adenomas were significantly higher in endometrial cancer than normal controls. Colonoscopic evaluation of whole colon will be recommanded in gynecologic cancer than sigmoidoscopy.
, Sung Ae Jung, Min A Yu, Young Ju Choi, Ji Yoon Cho, Su Hyun Kim, Kwon Yoo, Il-Hwan Moon The aim of this study was to evaluate the clinicopathologic characteristics of the colorectal polyps in people under 50 years old.
From January to August 2001, the colonoscopic finding and pathologic reports of 527 patients under 50 years old who underwent colonoscopy were reviewed retrospectively. The advanced polyp was defined as an adenoma more than 10mm in diameter or with the histology of villous or high grade dysplasia.
Total 94 colonic polyps(17.8%) were analyzed. On age distribution, 65 cases(69.1%) were in forth decade, 25 cases(26.6%) in third decade. Abdominal pain(29.8%) was the most common cause of taking the colonoscopic examination followed by rectal bleeding(18.1%), asymptomatic screening(12.7%). Rectosigmoid area was the most common site of polyps in 63.8%. On the pathologic review, adenoma was found 55.1%, inflammatory polyp 38.5% and hyperplastic polyp 6.4%. Advanced adenomas were 17.9%(17/156) and adenomas with focal carcinomatous changes were 1.9%(3/156). Patients who had symptoms of abdominal pain or rectal bleeding, multiple polyps or familial history of colorectal cancer had a higher prevalence of advanced adenoma than that of non-advanced adenoma(
This study showed that major symptoms of patients with advanced polyps under 50 years old were abdominal pain and rectal bleeding. The symptoms, multiplicity of polyp and family history were important indicator of advanced polyps. Further study was needed for reasonable indication and cost effectiveness for colonoscopic examination in young age people.
, Wha Jeong Kim, Do Yeon Kim, Jeong Eun Shin, Tae Hee Kim, Soo Young Park, Jun Sik Nam, Sung Hun Park, Hong Keun Cho Heat stoke is a life-threatening syndrome of multi-organ dysfunction caused by elevated body temperature. Reported mortality rate range from 17-70 percent. The heat stoke victim's circulatory pattern id defined low peripheral vascular resistance and high circulatory demand of other conditions involving tissue injury such as trauma or sepsis. Owing to either to direct thermal injury of the myocardium or to increased pulmonary vascular resistance, the heart may not meet the elevated circulatory demand. Heat stoke induced cardiomyopathy is diagnosed by pathlogy, EKG abnormality, LDH isoenzyme, echocardiography. Therapy was two purpose : rapid reduction of body temporature and support of the cardiovascular system. We experienced a case of heat stoke induced cardiomyopathy in a 21 year-old male who had been observed for 1 years. The Left Ventricular End-Diastolic Diameter(LVEDD) was 65mm, Ejection fraction(EF) was 35% initially and LVEDD was decreased 58mm, EF was 60% after 9 months. We report a case of heat stoke induced cardiomyopathy with brief review of literature.
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