, Min-Jung Kang, Soyun Cho, Kyu-Kwang Whang, Jeong-Hee Hahm The field of dermatologic surgery has seen trementdous developments in the past few years.
Our purpose was to discuss current statistical data on the dermatologic patients treated by surgical methods at our institute.
We analyzed 2,334 cases of surgeries performed on 1,075 patients at the Department of Dermatology of Ewha Womans University Tongdaemun Hospital during a period of 5 years (1994. 1 - 1998. 12).
The results are summarized as folows:
1) Of the 2,334 cases of surgeries, 846 cases(36.2%) were chemical peelings, 650 cases(27.8%) cryosurgeries, 255 cases(10.9%) CO2, lasers, 209 cases(8.9%) dermabrasions, 113 cases(4.8%) scalpel surgeries, 61 cases(2.6%) Mohs micrographic surgeries, 50 cases(21.1%) sclerotherapy, 48 cases(2.0%) flap repair surgeries, 35 cases(1.5%) punch elevations, 15 cases(0.6%) hair transplantations, 13 cases(0.5%) epidermal grafts, and 2 cases(0.1%) autologous fat/collagen transplantations.
2) The ratio of male to female was 1 : 2.4 and the mean age of patients was 30.3 years.
3) A total of 1,354 cases of diseases were managed surgically : among them, the most frequent disease was scar(39.8%), followed by pigmentary disorders(30.8%), and benign or malignant tumors(21.2%).
4) With respect to the types of scars, acne scar was treated most frequently by chemical peeling (72.7% of 580 cases), atrophic scar by dermabrasion(37.3% of 126 cases), and hypertrophic scar (including burn scars) by cryosurgery(35.3% of 85 cases).
, Youn-Jin Kim, Hyun-Joo Kim, Soyun Cho, Kyu-Kwang Whang, Jeong-Hee Hahm We report a case of type III hyperlipoproteinemia associated with tuberous xanthoma, which is improved by treatment with lovastatin and bezafibrate. A 34-year-old female patient visited our clinic for evaluation of multiple yellowish-brown papulonodules on the kness, elbows and palms. Serum lipid examination showed an abnormal elevation of serum cholesterol and triglyceride. Lipoprotein electrophoresis showed a single peak at pre-β and β portion without separation. The biopsh specimen from a nodule on the knee and a papule on the palm revealed characteristic findings of xanthoma. We diagnosed the case as type III hyperlipoprotei-nemia. After 3 months of treatment with diet restriction, lovastatin and bezafibrate, the serum levels of cholesterol and triglyceride were reduced to normal level. The skin lesion of the palm showed complete regression and ones on both knees and elbows were moderate improvement.
, Moon-Jung Kim, Soyun Cho, Kyu-Kwang Whang, Jeong-Hee Hahm This study attempts to evaluate the clinical manifestations and causative drugs of drug eruptions at Ewha Womans University Tongdaemun Hospital by retrospective study of outpatients, inpatients and consulted patients(number : 121, duration : 1994. 1 - 1999. 5).
1) Most drug eruptions occurred in patients at the age of 20 - 39 years old.
2) The cutaneous manifestations of drug eruptions in the order of frequency were as follows : exanthematous eruption, fixed drug eruption, acneiform eruption, purpura, urticaria, bullous eruption, lichenoid eruption, Stevens-Johnson syndrome, and acute generalized exanthemic pustulosis.
3) Drug eruption developed most frequently from 24 hours to 3 days of drug intake.
4) Most common causative drugs were antibiotics, followed by antipyretics and analgesics.
5) Laboratory abnormalities were leukocytosis(22.5%), eosinophilia(14.5%), abnormal AST/ALT(11.4%), abnormal IgE titer(8.3%), and leukopenia(5.6%).
The most frequent clinical feature of the drug eruption were exanthematous in nature and the most common causative drugs were antibiotics, as suspected.
Since too many patients take various unidentified drugs at drug stores in Korea, physicians need to exercise special care in prescribing drugs and evaluating patients with drug eruption.
, So-Yun Cho, Ho-Jung Kang, Jeong-Hee Hahm This study was performed to investigate the clinical manifestations and laboratory findings, and to see whether the severity of atopic dermatitis(AD) implies a relationship to the clinical and laboratory findings.
Our study was designed by analyzing outpatients with AD via physical examination, questionnaires and laboratory investigations such as prick test to house dust mites, bacterial cultures, total IgE, IgA, IgG, IgG4, IgM, and peripheral eosinophil count.
1) Xerosis, ear fissuring and hyperlinear palms were related to the severity of AD(p<0.05). 2) Sweating, foods and aeroallrgen were related to the severity of AD(p<0.05). 3) The presence of family history of AD differed significantly(p<0.05) between the severe group(57.9%) & the mild group(26.3%). 4) The positivity of the prick test to Dermatophagoides pteronyssinus and D.farinae was found in 90.0% of respiratory group and in 30.0% of AD only(p<0.05%). 5) Serum IgE level was higher in the severe group(938.3±601.8 IU/mL) than the mild group(526.7±352.1IU/mL)(p<0.05). 6) Serum IgE level in AD patients with respiratory disease(1025.8±713.2IU/mL) was higher than AD only(403.3±273.4IU/mL)(p<0.05). 7) Peripheral eosinophil counts were higher in the severe group(509.9±389.4/mm3) than the mild group(340.5±219.4/mm3)(p<0.05).
The factors related to severity of AD were xerosis, ear fissuring, hyperlinear palms, sweating, food, aeroallergen, serum IgE and peripheral eosinophil count. The AD patients with respiratory allergic disease had higher IgE levels and higher positive rates of prick test with house dust mite.
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