This study investigated the correlations between childhood sexual abuse and the severity of psychopathology symptoms in adulthood and the usefulness of adult psychiatric symptoms, diagnoses, and medications as factors in the identification of patients who have been sexually abused in childhood.

The subject of this study were 21 childhood sexually abused female inpatients and 22 nonabused female inpatients(psychiatric control group). All subjects were interviewed and completed self report instruments that focused of childhood sexual histoy of trauma, and current general psychiatric symptoms, dissociative symptoms.

Sexually abused broup showed significantly higher rates of divorce than psychiatric control group. Relative to psychiatric control group, sexually abused group have more hospitalization, higher proportion of more suicidal symptoms and more often major pharmacological tratment. Sexually abused group manifested significantly higher levels of dissociative symptoms and general psychiatric symptoms, including interpersonal sensitivity, psychoticism, obsessive compulsive and global severity index.

Findings suggest that childhood sexual abuse is associated with adult psychiatric symptoms, especially dissociative symptoms and work as etiology of psychopathology of boderline personalitiy disorder.

Tumor lysis syndrome(TLS) has been broadly defined as the metabolic abnormalities that occur after rapid tumor breakdown. The purpose of this study was to evaluate the types or degrees of metabolic abnormalities and clinical characteristics in patients with high-grade non-Hodgkin's lymphoma(NHL) who developed clinical TLS.

Patients were considered to have 'clinical TLS' if two of the following metabolic abnormalities occurred within 4 days of treatment : a 25% increase in the serum phosphate, potassium, uric acid, urea nitrogen concentrations, or a 25% decline in the serum calcium concentration and one of the following : a serum potassium level greater than 6.0mEq/L, a creatinine level greater than 2.5mg/dL, a calcium level less than 6.0mg/dL, the development of a life-threatening arrhythmia, or sudden death.

Clonical TLS occurred in 15 patients with advanced high-grade NHL, and these patients were associated with elevated lactate dehydrogenase(LDH) and β₂-mivtonlonulin(MG)levels. Pre-treatment TLS occurred in 10 patients(66.7%) and post-treatment TLS in 5 patients(33.3%). Most of these patients showed metabolic abnormalities including hyperuricemia, hyperphosphatemia, hypocalcemia, or acute renal insufficiency. They were treated with adequate hydration combined with allopurinol and recovered in 4 patients. In remained 11 patients, hemodialysis was required and the metabolic parameters returned to normal levels without any significant complications.

It is important to remember that patients with advanced high-grade NHL who have more increased serum LDH or β₂-MG level be carefully monitored. Further investigations of elucidating risk factors and diagnostic criteria on clinical TLS will be required.