, Tae-Hun Kim, Min-sun Ryu, Da-Yeon Oh, Myung-Eun Song, Shina Lee, Jae-In Ryu, Hye-In Kim, Il-Hwan Moon, Kwon Yoo The causes of pyogenic liver abscess has been known as biliary tract disease or intrabadominal infection but the large proportions of the patients has no apparent underlying disorders. Recently colonic mucosal lesions were reported in patients with cryptogenic liver abscess and it has been suggested that colonic mucosal break may play a role in developing liver abscess in otherwise healthy patients. We experienced a patient of severe recurrent liver abscess complicated with endophthalmitis only 3 months after successful treatment of initial cryptogenic liver abscess and a polypoid colon cancer was discovered by chance. It seems prudent to proceed colonoscopic examination in patients with cryptogenic liver abscess especially when it is recurrent.
, Chang Yoon Ha, Hyun Jeong Jang, Eun Young Yun, Ji Hyun Ju, Yeon Jeong Ahn, Hyun Ju Min, Tae Hyo Kim, Hyun Jin Kim, Woon Tae Jung, Ok Jae Lee, Sun Young Yi A 55-year-old man was admitted to our hospital with symptom of fever, chilling, abdominal discomfort and weight loss for 2months. Abdominal computed tomography(CT) revealed a 5×3.75 cm sized low attenuated lesion in the left lateral segment of liver. Esophagogastrodedodenoscopy showed a fistula with dirty exudates at the fundus and a yellowish stone and food debris at the choledochoduodenostomy site. Endoscopic retrograde cholangiopancreatography (ERCP) was performed and stone and food materials in common bile duct was removed with snare and basket. We experienced a case of liver abscess due to sump syndrome and spontaneous drainage to the stomach.
Pyogenic liver abscess is a potentially life-threatening disease with substantial mortality rate. With the recent advances in diagnostic modalities and new treatment strategies, the overall mortality of pyogenic liver abscess has been decreased significantly but stillhigh mortality rates are recorded in patients with old age, multiple abscesses, malignant biliary obstruction and inadequate drainage. Therefore pyogenic liver abscess remains a major clinical challenge. We are going to investigate the current clinical features of pyogenic liver abscess.
Medical records of those who admitted to the Ewha Womans University Mokdong Hospital since 1993 and diagnosed as having Pyogenic liver abscess were reviewed. A total of 88 pyogenic liver abscess patients was detected and their clinical presentation, bacteriologic etiologies, comorbidities and treatment results were investigated.
Fifty male and 38 female (1.3 :1) patients were enrolled and the mean age was 59years. The most common presenting symptom was fever/chill (77%) followed by abdominal pain(64%), nausea/vomiting (42%) and general weakness (41%). Diabetes mellitus was combined in 17% of the patients and most of pyogenic liver abscesses were induced by ascending biliary infection (43%) or unknown cause (52%). Leukocytosis was evident in 74% of the patients and elevated akaline phosphatase in 52%. Sixty five percent of the abscess cavities were located inright lobe of the liver and most of them were solitary (73%). Pus culture was more efficient than blood culture for the detection of causative microorganis and
Rapid diagnosis of pyogenic liver abscess can be done through a complete history taking, physical examination and a prompt imaging studies and aggressive application of percutaneous aspiration or drainage of the abscess cavity with the empirical antibiotic administration targetting gram-negative aerobe may contribute to the improvement of the mangement of pyogenic liver abscess.
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