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"Lung neoplasm"

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[English]
Impact of pulmonary tuberculosis on lung cancer screening: a narrative review
Jeong Uk Lim
Received February 16, 2025  Accepted March 17, 2025  Published online March 26, 2025  
DOI: https://doi.org/10.12771/emj.2025.00052    [Epub ahead of print]
Lung cancer remains a leading cause of cancer-related mortality worldwide. Low-dose computed tomography (LDCT) screening has demonstrated efficacy in reducing lung cancer mortality by enabling early detection. In several countries, including Korea, LDCT-based screening for high-risk populations has been incorporated into national healthcare policies. However, in regions with a high tuberculosis (TB) burden, the effectiveness of LDCT screening for lung cancer may be influenced by TB-related pulmonary changes. Studies indicate that the screen-positive rate in TB-endemic areas differs from that in low-TB prevalence regions. A critical challenge is the differentiation between lung cancer lesions and TB-related abnormalities, which can contribute to false-positive findings and increase the likelihood of unnecessary invasive procedures. Additionally, structural lung damage from prior TB infections can alter LDCT interpretation, potentially reducing diagnostic accuracy. Nontuberculous mycobacterial infections further complicate this issue, as their radiologic features frequently overlap with those of TB and lung cancer, necessitating additional microbiologic confirmation. Future research incorporating artificial intelligence and biomarkers may enhance diagnostic precision and facilitate a more personalized approach to lung cancer screening in TB-endemic settings.
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Case Reports
[English]
Stress-induced Cardiomyopathy Associated with Non-Small Cell Lung Cancer Presenting as Hyponatremia
Jong Taek Kim, Seok Ho Seo, Seung Hyun Lee, Dae Won Park, Dong Goo Kang, Seung Uk Lee
Ewha Med J 2015;38(2):90-93.   Published online July 29, 2015
DOI: https://doi.org/10.12771/emj.2015.38.2.90

Stress-induced cardiomyopathy, so-called Takotsubo cardiomyopathy, has recently been reported in Japan. Stress-induced cardiomyopathy is characterized by transient left ventricular apical dysfunction and ballooning, with normal coronary angiographic findings. We describe a rare case of stress-induced cardiomyopathy associated with lung adenocarcinoma presenting as hyponatremia.

Citations

Citations to this article as recorded by  
  • Hyponatremia and takotsubo syndrome: a review of pathogenetic and clinical implications
    Kenan Yalta, Orkide Palabıyık, Muhammet Gurdogan, Ertan Yetkın
    Heart Failure Reviews.2023; 29(1): 27.     CrossRef
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  • 1 Crossref
[English]
Metastatic Pulmonary Mucoepidermoid Carcinoma with Fulminant Clinical Course
Yong Won Park, Seon Bin Yoon, Mi Ju Cheon, Young Min Koh, Hyeon Sik Oh, Se Joong Kim, Seung Hyeun Lee
Ewha Med J 2015;38(2):85-89.   Published online July 29, 2015
DOI: https://doi.org/10.12771/emj.2015.38.2.85

Pulmonary mucoepidermoid carcinoma (MEC) is a rare form of lung cancer that originates from submucosal glands of tracheobronchial tree. Unlike low-grade tumor with benign nature, high-grade case is even rarer and has aggressive clinical features with no definite treatment option. Here, we report a case of high-grade pulmonary MEC with fulminant clinical course. A 74-year-old man presented with cough, sputum and mental change. Chest imaging showed massive mediastinal lymphadenopathy with obstructive pneumonia, and multiple metastases in lung and adrenal gland. Bronchoscopy showed polypoid masses obstructing right main bronchus and bronchus intermedius. Histopathology revealed a mixture of glandular structure lined with mucussecreting cells and nests of squamoid cells with nuclear atypia and pleomorphism, which is compatible with high-grade MEC. We intensively treated the patient with combination antibiotics and ventilator care. However, the patient did not respond to the treatment and rapidly deteriorated, and finally expired a month after diagnosis.

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[English]
Anesthetic Management for Lung Adenocarcinoma Experienced Acute Neurocardiogenic Syncope and Cardiac Arrest
Jin Hye Han, Youn Jin Kim, Jong Hak Kim, Dong Yeon Kim, Guie Yong Lee, Chi Hyo Kim
Ewha Med J 2014;37(Suppl):S28-S32.   Published online December 24, 2014
DOI: https://doi.org/10.12771/emj.2014.37.S.S28

Vasovagal syncope is one of the most common causes of transient syncope during anesthesia for elective surgery in patients with a history of syncope and requires special attention and management of anesthetics. The causes and pathophysiological mechanism of this condition are poorly understood, but it has a benign clinical course and recovers spontaneously. However, in some cases, this condition may cause cardiovascular collapse resulting in major ischemic organ injury and be life threatening. Herein we report a case and review literature, regarding completing anesthesia safely during an elective surgery of a 59-year-old female patient with history of loss of consciousness due to suspected vasovagal syncope followed by cardiovascular collapse and cardiac arrest, which required cardiopulmonary resuscitation and insertion of a temporary pacemaker and intra-aortic balloon pump immediately after a fine-needle aspiration biopsy of a lung nodule located in the right middle lobe.

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