Vaginal pH change is known as one of the risk factors for recurrent lower urinary tract infection in female. The objective of this study was to analyze the correlation between lower urinary tract infection & overactive bladder revelation and vaginal pH by age group.

Subjects were schizophrenic out-patients, who fufilled DSM-IV diagnostic criteria, and their families.

This study found a positive correlation between age and vaginal pH(p=0.000). It also found that the contraction of cystitis patients was high in older age group(p=0.035). However, vaginal pH was not a significant factor to the contraction of cystitis(p=0.258). In older age group, the number of overactive bladder patients was higher than that of younger age group(p=0.05), while vaginal pH was not a significant factor to the contraction of overactive bladder(p=0.376).

Diseases that cause lower urinary tract symptom such as overactive bladder and recurrent cystitis increase in proportion to age. Vaginal pH also increases in proportion to age. However, vaginal pH is not a significant factor to the contraction of lower urinary tract symptom when the age is revised.

Overactive bladder(OAB) is a symptom syndrome including urinary urgency with or without urinary incontinence, usually combined with frequency and nocturia. There are lots of reports concerning the first-line treatment for OAB, the treatment is still challenging. Extracorporeal magnetic innervation(ExMI) therapy have been known to be safe and effective immediately in stress urinary incontinence and OAB. The aim of this study was to assess the effect of suprapubic magnetic innervation therapy by arm-typed plate in patients with OAB.

The selected subjects were 32 patients diagnosed with OAB between the periods of April to September, 2007. Mean age was 48.3±10.7 years old, and there were 10 males and 22 females patients. Voiding diary, International Prostatic Symptoms Score(IPSS), quality of life(QOL) questionnaire were evaluated as assessment of voiding symptoms. The treatment was performed for 15 minutes, 2 times a week, for 6 weeks with ExMI by arm-typed plate(BioCon-2000. M-Cube, Korea). All of the evaluations were repeated immediately and 3 months after treatment.

The mean urgency episodes decreased from 13.2±1.81 times to 8.7±1.95 times immediately after treatment and 9.6±2.18 times at 12 weeks after treatment(p<0.05). At 6 weeks after starting treatment, the mean frequency decreased from 5.4±1.58 times to 3.6±1.37 times(p<0.05), but the mean frequency after 6 months was 4.3±1.72 times(p>0.05). Significant improvements immediately after treatment were noted in the frequency, urgency, and QOL in IPSS, which were maintained for 3 months(p<0.05). There were improvements in mean voided volume, but these were minimal.

The symptoms of OAB are highly prevalent and significantly affect the quality of life. Effective and prompt management of OAB should be implemented. Our datas suggested that the EXMI therapy by arm-typed plate has the favorable effect on OAB and it may be persist for at least 12 months. Further studies are needed to establish the long-term efficacy of EXMI therapy in patients with symptoms of OAB.