Pemphigus erythematosus(Senear-Usher syndrome) was originally described by Senear and Usher as a type of pemphigus with features of lupus erythematosus. We present two cases of pemphigus erythematosus on the face and trunk. The case 1 was a 41-year-old female who have had erythematous scaly patches and a few flaccid bullae, and treated by corticosteroids and azathioprine. The case 2 was a 42-year-old male who have had same lesions and treated by corticosterids.