Thrombohemorrhagic complications in chronic myeloproliferative disease(CMPD) including chronic myelogenous leukemia(CML) are not rare. Lower incidence of disordered hemostasis is reported in CML compared with other CMPD. The mechanism of thrombohemorrhagic complications might be a consequence of qualitative platelet abnormalites and prolonged bleeding time rather than that of thrombocytosis. Although defect of platelet function has been extensively investigated, there was no established consistent correlation between clinical bleeding and number and function of platelet. The most common site of bleeding complications in the CMPD is superficial mucosa. Bleeding in deep tissue and viscera is very unusual. We report a case of CML which developed a huge spontaneous retroperitoneal hematoma.

Clinical studies have indicated that the non-operative treatment is the best method for clavicle fracture and the operative treatment may contribute to the development of non-union. But some clavicle fractures may be difficult to treat only by non-operative method.

From March, 1980 to May, 1989, 42 patients with clavicle fractures were treated by open reduction and internal fixation with threaded steinmann pin and plate & screws at Department of Orthopaedic Surgery of Ewha Womans University Hospital.

The results were as follows;

1) The avarage duration of union of fracture was 6.7 weeks.

2) By open reduction & internal fixation, gross deformity such as large bone hypertrophy, joint stiffness and shortening was minimized.

3) The plate & screws fixation is more satisfactory result than threaded steinmann pin fixation.