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"Sun Hong Yoo"

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"Sun Hong Yoo"

Case Reports
[English]
Night Blindness Induced by Long-term External Bile Drainage
Seung Min Lee, Jin Young Choi, Ho Jun Kang, Ji Hee Sung, Sang Jong Park, Sun Hong Yoo, Young Min Park
Ewha Med J 2015;38(1):42-45.   Published online March 26, 2015
DOI: https://doi.org/10.12771/emj.2015.38.1.42

Vitamin A deficiency can occur as a result of malnutrition, malabsorption, or poor vitamin metabolism due to liver disease and night blindness might develop as the first symptom. Although there have been foreign reports about night blindness due to vitamin A deficiency which was derived from liver cirrhosis, primary biliary cirrhosis, intestinal bypass surgery or bariatric operation, it is hard to find reports about night blindness after percutaneous transhepatic biliary drainage for external bile drainage. We report a case of night blindness derived from fat-soluble vitamin A deficiency developed after long-term (18 months) external bile drainage for benign biliary stricture occurred after left hepatic lobectomy and hepaticojejunostomy due to the Klatskin tumor (IIIb). Her night blindness and low serum retinol level (0.02 mg/L) was dramatically improved after vitamin A supplementation. We recommend lipid-soluble vitamin supplementation on the case of long-term external bile drainage.

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[English]
Chelidonium majus-Induced Acute Hepatitis
Sung Gyu Im, Sun Hong Yoo, Dong Ok Jeon, Hyo Jin Cho, Jin Young Choi, Soya Paik, Young Min Park
Ewha Med J 2014;37(1):60-63.   Published online March 25, 2014
DOI: https://doi.org/10.12771/emj.2014.37.1.60

The use of traditional folk remedies is increasing throughout Asia. Chelidonium majus, a popular herbal remedy, is used to treat abdominal pain caused by various gastrointestinal disorders, including gastric ulcer, gastritis, and biliary tract disease, because of its morphine-like effect. We encountered a 62-year-old woman with acute hepatitis, in which C. majus was suspected to be the etiological factor. The patient had taken high dose of C. majus extract for the preceding 60 days. The clinical context and the temporal association between the start of the herbal medicine treatment and her liver injury allowed us to attribute a causative role to C. majus. The diagnosis was confirmed by liver biopsy and the Council for International Organizations of Medical Sciences/Roussel Uclaf Causality Assessment Method (CIOMS/RUCAM) scale. After C. majus was discontinued, the liver function was restored to normal. In conclusion, because the use of phytotherapy is increasing, we wish to raise awareness of the potential adverse effects of C. majus.

Citations

Citations to this article as recorded by  
  • A Hidden Cause of Hypertransaminasemia: Liver Toxicity Caused by Chelidonium Majus L.: Report of Two Cases of Herb-Induced Liver Injury and Literature Review
    Vera Ciornolutchii, Abdulrahman Ismaiel, Cristina Maria Sabo, Nadim Al Hajjar, Andrada Seicean, Dan L. Dumitrascu
    American Journal of Therapeutics.2024; 31(4): e382.     CrossRef
  • Traditionally Used Medicinal Plants of Armenia
    Arpine Ayvazyan, Christian Zidorn
    Plants.2024; 13(23): 3411.     CrossRef
  • Ethnobotanical Knowledge in Sete Cidades, Azores Archipelago: First Ethnomedicinal Report
    Pedro T. M. Silva, Marta A. F. Silva, Luís Silva, Ana M. L. Seca
    Plants.2019; 8(8): 256.     CrossRef
  • Total Synthesis of the Proposed Structure of Turkiyenine
    Hisataka Kobayashi, Yusuke Sasano, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
    European Journal of Organic Chemistry.2016; 2016(2): 270.     CrossRef
  • RUCAM in Drug and Herb Induced Liver Injury: The Update
    Gaby Danan, Rolf Teschke
    International Journal of Molecular Sciences.2015; 17(1): 14.     CrossRef
  • Chelidonium majus

    Reactions Weekly.2014; 1508(1): 12.     CrossRef
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