Emphysematous pyelonephritis is an uncommon serious suppurative infection, characterized by the production of intrarenal and perirenal gas and can occur in patients with diabetes mellitus or urinary obstruction.

We report our experience with successful management of a case of emphysematous pyelonephritis which occurred in 43 years-old diabetic woman with sepsis and liver cirrhosis. Left nephrectomy was carried out to cure septic crisis.