, Yon Ju Ryu, Hye Won Kang, Doo Hyun Baek, Soo Hyun Kim, Min Young Choi, Hye Sung Park, Jin Hwa Lee, Eun-Mi Chun, Jung Hyun Chang, Young Joo Cho, Yoon Hee Jun, Sung Shine Shim, Miae Lee , Sun Young Yi, In Jeong Cho, Hye Sung Won, Yoon Hee Jun, Seung Hyun Yoo , Tae Hun Kim, Kum Hei Ryu, So Yeon Lim, Ju Ho Lee, Shi Nae Lee Hepatoid adenocarcinoma was described by Ishikura in 1985 for the first time. It is a very rare variant of adenocarcinoma characterized by morphological and functional features of hepatocyte differentiation. It is most commonly presented as gastric adenocarcinoma with otherwise unexplained elevation of serum alpha-fetoprotein level. Most of the patients with gastric hepatoid adenocarcinoma were diagnosed in advanced stages having vascular invasion and/or extensive metastasis in liver or lymph nodes. Accordingly, the prognosis of hepatoid adenocarcinoma is dismal. We experienced a typical case of gastric hepatoid adenocarcinoma and described the clinical features.
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