Case Report

A Case of Microperforation after Endoscopic Duodenal Biopsy

Young Wook Noh, Sung-Ae Jung, Hyun Joo Song, Jae Jung Park, Kyung Jong Lee, Eun Kyung Baek, Seog Ki Min*
Author Information & Copyright
Department of Internal Medicine, Ewha Medical Research Institute, Korea.
*General Surgery, Ewha Womans University School of Medicine, Korea.

Copyright ⓒ 2008. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Sep 30, 2008


Nowadays, upper gastrointestinal endoscopy is very commonly performed procedure as a diagnostic tool or therapeutic purpose. Although perforation rate during diagnostic evaluation has been reported as low about 0.03%, gastrointestinal perforation is a critical problem to the patients owing to significant morbidity and hospital stay. Therefore, all endoscopists should know the risk factors for the perforation and pay attention to avoid this complication. We experienced a case of 66 year-old-male with duodenal microperforation after endoscopic biopsy. During endoscopic examination, a submucosal mass was detected at duodenal second portion and endoscopic biopsy was performed. After this, he complained of severe abdominal pain during colonoscopy. Emergent simple abdomen and abdominal computed tomography revealed multiple free air in retroperitoneal space and duodenal perforation was suspicious. He was treated with primary closure and then recovered completely. Therefore, we report a case with microperforation after endoscopic duodenal biopsy.

Keywords: Endoscopic biopsy; Duodenal perforation